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Structure of 1807505-29-8
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Br-PEG4-CH2-Boc features a bromide-functionalized PEG4 spacer linked to a Boc-protected amine via a methylene bridge. This bifunctional reagent enables site-specific conjugation in synthetic chemistry, combining excellent solubility with orthogonal protection. The pendant bromide facilitates nucleophilic substitution, while the Boc group remains stable under basic conditions and can be selectively removed for downstream coupling.
Br-PEG4-CH2-Boc serves as a versatile bifunctional building block for conjugation and protection strategies in synthetic organic chemistry. The bromide group enables efficient nucleophilic substitution reactions, while the PEG4 spacer provides solubility and reduced aggregation. The Boc group offers reliable protection of primary amines, removable under mild acidic conditions. This compound facilitates site-specific derivatization in peptide synthesis, macrocycle formation, and the construction of bioconjugates with enhanced stability and handling properties.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: