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CS-W001157 4
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Ethyl 4-amino-1-methyl-1H-imidazole-2-carboxylate hydrochloride

  • CAS No. 180258-46-2

  • Cat. No. CS-0099802
  • Purity≥97%
  • MDL No.MFCD01318760

*For research and further manufacturing use only, not for direct human use.

Ethyl 4-amino-1-methyl-1H-imidazole-2-carboxylate hydrochloride|CS-0099802

Structure of 180258-46-2

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General Information

  • CAS No. 180258-46-2
  • Cat. No. CS-0099802
  • Purity ≥97%
  • MDL No. MFCD01318760
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₂ClN₃O₂
  • Molecular Weight 205.64
  • Synonym(s) 4-AMINO-1-METHYL-1H-IMIDAZOLE-2-CARBOXYLIC ACID ETHYL ESTER HCL
  • SMILES O=C(C1=NC(N)=CN1C)OCC.[H]Cl

Description

Ethyl 4-amino-1-methyl-1H-imidazole-2-carboxylate hydrochloride features a protonated imidazole core with a methyl group at C1 and an ethyl ester at C2, delivering enhanced solubility and stability under standard conditions. The 4-amino substituent enables facile derivatization in synthetic sequences.

Application

Ethyl 4-amino-1-methyl-1H-imidazole-2-carboxylate hydrochloride serves as a versatile building block in medicinal chemistry, enabling efficient access to imidazole-based scaffolds. Its amine and ester functionalities support diverse transformations, including amidation, coupling reactions, and cyclization processes. The hydrochloride salt enhances bench stability and solubility, facilitating handling and purification in standard synthetic workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   70.14
  • LogP   0.6008
  • H_Acceptors   5
  • H_Donors   1
  • Rotatable_Bonds   2

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