(R)-3-(1-Aminoethyl)phenol hydrochloride

Name: (R)-3-(1-Aminoethyl)phenol hydrochloride
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CAS No. 856563-08-1
Cat. No. CS-0131596
Purity≥95%
MDL No.MFCD11044547

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

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(R)-3-(1-Aminoethyl)phenol hydrochloride|CS-0131596

Structure of 856563-08-1

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General Information

CAS No. 856563-08-1
Cat. No. CS-0131596
Purity ≥95%
MDL No. MFCD11044547
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₈H₁₂ClNO
Molecular Weight 173.64
Synonym(s) 3-(1-Aminoethyl)phenol hydrochloride
SMILES N[C@H](C)C1=CC(O)=CC=C1.[H]Cl

Description

(R)-3-(1-Aminoethyl)phenol hydrochloride is a chiral phenolic amine featuring a stereodefined α-amino alcohol moiety. This bench-stable, moisture-tolerant compound integrates readily into asymmetric synthesis workflows, serving as a key building block for bioactive molecule development. The para-hydroxyl group enables direct functionalization or metal coordination, while the protonated amine ensures solubility and ease of purification under standard conditions.

Application

(R)-3-(1-Aminoethyl)phenol hydrochloride serves as a chiral building block for the synthesis of bioactive aryl ethylamine derivatives. Its stable hydrochloride salt form enhances bench handling and storage, while the ortho-phenolic functionality enables direct coupling or derivatization in standard synthetic workflows. The (R)-configured stereocenter supports enantioselective transformations relevant to pharmaceutical intermediates, with tolerance to common functional groups under mild reaction conditions.

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

TPSA 46.25
LogP 1.8337
H_Acceptors 2
H_Donors 2
Rotatable_Bonds 1

Other Classifications

Building Blocks Functional Group Phenol

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Key Words

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(R)-3-(1-Aminoethyl)phenol hydrochloride

CAS No. 856563-08-1

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