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Structure of 1255666-86-4
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This protected piperidine derivative features a difluorinated ring system and a tert-butyl carbamate group, enabling stable incorporation into peptide-based scaffolds. The electron-withdrawing fluorine atoms enhance conformational rigidity and metabolic stability, while the Boc moiety permits selective deprotection during synthetic workflows.
1-(tert-Butoxycarbonyl)-5,5-difluoropiperidine-3-carboxylic acid serves as a valuable building block in medicinal chemistry, enabling the incorporation of a sterically constrained, electron-deficient piperidine scaffold. The difluoro substitution at C5 enhances metabolic stability and modulates basicity, while the Boc group provides orthogonal protection for amine functionality. This compound facilitates efficient coupling reactions and subsequent deprotection, supporting streamlined synthesis of fluorinated heterocyclic motifs common in bioactive molecules.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: