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CS-W001157 4
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5-Azaspiro[2.5]octane hydrochloride

  • CAS No. 1797157-33-5

  • Cat. No. CS-0138597
  • Purity≥97%
  • MDL No.MFCD26936190

*For research and further manufacturing use only, not for direct human use.

5-Azaspiro[2.5]octane hydrochloride|CS-0138597

Structure of 1797157-33-5

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General Information

  • CAS No. 1797157-33-5
  • Cat. No. CS-0138597
  • Purity ≥97%
  • MDL No. MFCD26936190
  • Storage Store at room temperature, keep dry and cool
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₄ClN
  • Molecular Weight 147.65
  • Synonym(s) 5-aza-spiro[2.5]octane hydrochloride
  • SMILES [H]Cl.C1CC12CNCCC2

Description

5-Azaspiro[2.5]octane hydrochloride features a rigid, bicyclic scaffold that imparts conformational stability and enhances bioavailability. This nitrogen-containing spirocycle serves as a privileged heterocyclic core in medicinal chemistry, offering favorable solubility and metabolic resistance. The hydrochloride salt form improves crystallinity and handling properties for synthetic applications.

Application

5-Azaspiro[2.5]octane hydrochloride serves as a rigid, nitrogen-containing heterocyclic scaffold with well-defined stereochemistry, enabling efficient access to spirocyclic architectures in medicinal chemistry. Its stability under standard reaction conditions and compatibility with diverse functional groups facilitate downstream derivatization. The hydrochloride salt enhances solubility and handling for bench-scale synthesis, making it a practical building block for targeted compound libraries and API intermediates.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   12.03
  • LogP   1.5718
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   0

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