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CS-W001157 4
Total: USD 88.00

5-Azaspiro[2.4]heptane hydrochloride

  • CAS No. 3659-21-0

  • Cat. No. CS-0058662
  • Purity≥95%
  • MDL No.MFCD21099571

*For research and further manufacturing use only, not for direct human use.

5-Azaspiro[2.4]heptane hydrochloride|CS-0058662

Structure of 3659-21-0

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General Information

  • CAS No. 3659-21-0
  • Cat. No. CS-0058662
  • Purity ≥95%
  • MDL No. MFCD21099571
  • Storage -20°C, protect from light, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₁₂ClN
  • Molecular Weight 133.62
  • Synonym(s) 5-azaspiro[4.2]heptane hydrochloride
  • SMILES N1CCC2(CC2)C1.Cl

Description

5-Azaspiro[2.4]heptane hydrochloride delivers a rigid, nitrogen-containing spirocyclic scaffold with enhanced solubility and stability under standard conditions. This bench-stable heterocycle integrates readily into medicinal chemistry libraries, offering a conformationally constrained core for probing target interactions in drug discovery programs.

Application

5-Azaspiro[2.4]heptane hydrochloride serves as a rigid, conformationally constrained scaffold for medicinal chemistry and synthetic organic applications. The bicyclic core enables precise spatial positioning of substituents, facilitating target-oriented synthesis of bioactive molecules. Its stability under standard reaction conditions and compatibility with diverse functional groups support efficient derivatization. The hydrochloride salt enhances solubility and handling, making it well-suited for high-throughput screening and process-scale synthesis.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   12.03
  • LogP   1.1817
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   0

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