tert-Butyl (2-methoxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)carbamate

Name: tert-Butyl (2-methoxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)carbamate
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 262433-02-3
Cat. No. CS-0168737
Purity≥97%
MDL No.None

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

tert-Butyl (2-methoxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)carbamate|CS-0168737

Structure of 262433-02-3

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 262433-02-3
Cat. No. CS-0168737
Purity ≥97%
MDL No. None
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₈H₂₈BNO₅
Molecular Weight 349.23
Synonym(s) 4-(TERT-BUTOXYCARBONYLAMINO)-3-METHOXYPHENYLBORONIC ACID, PINACOL ESTER
SMILES O=C(OC(C)(C)C)NC1=CC=C(B2OC(C)(C)C(C)(C)O2)C=C1OC

Description

tert-Butyl (2-methoxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)carbamate delivers a boronate handle flanked by a methoxy group and a bench-stable carbamate protecting group. This arylboron reagent integrates readily into Suzuki-Miyaura coupling reactions under standard conditions, enabling efficient construction of biaryl scaffolds with high functional group tolerance.

Application

tert-Butyl (2-methoxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)carbamate serves as a stable, bench-friendly boron building block for Suzuki-Miyaura cross-coupling reactions. The protected amine and methoxy group offer orthogonal functionality, enabling sequential transformations in complex molecule synthesis. Its high tolerance to diverse reaction conditions facilitates efficient C–C bond formation with aryl and vinyl halides, making it a practical reagent for constructing biaryl scaffolds in medicinal chemistry and materials science applications.

Synthesis

Route1
- In-stock
  
  73183-34-3
- In-stock
  
  262433-01-2
- ~65%
- In-stock
  
  262433-02-3
References
- CALDERWOOD, DAVID; ARNOLD, LEE; MAZDIYASNI, HORMOZ; HIRST, GAVIN C.; DENG, BOJUAN B.; JOHNSTON, DAVID N.; RAFFERTY, PAUL; TOMETZKI, GERALD B.; TWIGGER, HELEN L.; MUNSCHAUER, RAINER Patent: US2003/187001 A1, 2003 ; US 20030187001 A1
Route2
- In-stock
  
  461699-81-0
- In-stock
  
  24424-99-5
- ~64%
- In-stock
  
  262433-02-3
References
- Kressierer, Christoph J.; Lehnemann, Bernd; Jung, Jorg Patent: US2008/269523 A1, 2008 ; Location in patent: Page/Page column 6-7 ;

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 66.02
LogP 3.3414
H_Acceptors 5
H_Donors 1
Rotatable_Bonds 3

Other Classifications

Building Blocks Functional Group Amine

Building Blocks Functional Group Boronic Acid And Its Ester

Building Blocks Skeleton Aromatic ring compounds Benzene compounds

Key Words

262433-02-3 sigma262433-02-3 manufacturer262433-02-3 price262433-02-3 structure262433-02-3 SDSbuy 262433-02-3262433-02-3 supplier262433-02-3 uses262433-02-3 molecular weightprice of 262433-02-3262433-02-3 chemical name formula of 262433-02-3

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

tert-Butyl (2-methoxy-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)carbamate

CAS No. 262433-02-3

Recommended Products