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CS-W001157 4
Total: USD 88.00

2,2-Dimethoxyethanamine

  • CAS No. 22483-09-6

  • Cat. No. CS-0015304
  • Purity≥98%
  • MDL No.MFCD00008135

*For research and further manufacturing use only, not for direct human use.

2,2-Dimethoxyethanamine|CS-0015304

Structure of 22483-09-6

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General Information

  • CAS No. 22483-09-6
  • Cat. No. CS-0015304
  • Purity ≥98%
  • MDL No. MFCD00008135
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₄H₁₁NO₂
  • Molecular Weight 105.14
  • Synonym(s) Aminoacetaldehyde dimethyl acetal
  • SMILES COC(OC)CN

Description

Aminoacetaldehyde dimethyl acetal reacts with sulfone, followed by hydrolysis and reductive amination by adding desired piperazine derivative to yield piperazine derivatives of 2-furanyl[1,2,4]triazolo[1,5-a][1,3,5]triazine.Aminoacetaldehyde dimethyl acetal is used as a building block for the synthesis of various acylated and sufonylated oxyenamides.Aminoacetaldehyde dimethyl acetal was used in a study to develop a fluorescent substrate for aldehyde dehydrogenase. It was used in preparation of chitosan-dendrimer hybrids having various functional groups such as carboxyl, ester and poly(ethylene glycol). It was used in an efficient 3-step synthesis of a bicyclic proline analog from L-ascorbic acid and in 3-component reaction catalyzed by MgClO4 leading to -aminophosphonates.

Synthesis

  • Route1
    • 2,2-Dimethoxyacetonitrile|CS-0674580
      5861-24-5
    • ~%
    • In-stock
      2,2-Dimethoxyethanamine|CS-0015304
      22483-09-6

    References

    • Journal of the American Chemical Society, , vol. 77, p. 6640
  • Route2
    • null|null
      97-97-2
    • ~%
    • In-stock
      2,2-Dimethoxyethanamine|CS-0015304
      22483-09-6

    References

    • Journal of the American Chemical Society, , vol. 75, p. 3398
  • Route3
    • 2-(2,2-dimethoxyethyl)isoindoline-1,3-dione|CS-1006194
      27328-34-3
    • ~92%
    • In-stock
      2,2-Dimethoxyethanamine|CS-0015304
      22483-09-6

    References

    • Akalaeva, T. V.; Bokanov, A. I.; Ivanov, P. Yu.; Nikolaeva, I. S.; Pushkina, T. V.; et al. Pharmaceutical Chemistry Journal, 1989 , vol. 23, # 3 p. 231 - 234 Khimiko-Farmatsevticheskii Zhurnal, 1989 , vol. 23, # 3 p. 299 - 302

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS02,GHS05
Signal Word : Danger
UN#: 2734
Class : 8(3)
Packing Group : Ⅱ
Hazard Statements : H226-H314
Precautionary Statements : P210-P233-P240-P241-P242-P243-P260-P264-P280-P301+P330+P331-P304+P340-P363-P370+P378-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   44.48
  • LogP   -0.436
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   3

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