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CS-W001157 4
Total: USD 88.00

1-(Methylsulfonyl)spiro[indoline-3,4'-piperidine]

  • CAS No. 178261-41-1

  • Cat. No. CS-WAA0038
  • Purity≥95%
  • MDL No.MFCD04108105

*For research and further manufacturing use only, not for direct human use.

1-(Methylsulfonyl)spiro[indoline-3,4'-piperidine]|CS-WAA0038

Structure of 178261-41-1

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General Information

  • CAS No. 178261-41-1
  • Cat. No. CS-WAA0038
  • Purity ≥95%
  • MDL No. MFCD04108105
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₃H₁₈N₂O₂S
  • Molecular Weight 266.36
  • Synonym(s) 1-(Methylsulfonyl)-1,2-dihydrospiro[indole-3,4'-piperidine]
  • SMILES O=S(N1CC2(CCNCC2)C3=C1C=CC=C3)(C)=O

Synthesis

  • Route1
    • null|null
      184289-84-7
    • ~93%
    • 1-(Methylsulfonyl)spiro[indoline-3,4'-piperidine]|CS-WAA0038
      178261-41-1

    References

    • ELIXIR PHARMACEUTICALS, INC. Patent: WO2005/97788 A2, 2005 ; Location in patent: Page/Page column 86 ; WO 2005/097788 A2
  • Route2
    • Piperidine-4-carboxylic acid Avatrombopag Impurity|CS-0377512
      498-94-2
    • ~%
    • 1-(Methylsulfonyl)spiro[indoline-3,4'-piperidine]|CS-WAA0038
      178261-41-1

    References

    • Qi, Xian Liang; Yang, Er Qun; Zhang, Jun Tao; Wang, Tao; Cao, Xiao Ping Chinese Chemical Letters, 2012 , vol. 23, # 6 p. 661 - 664
  • Route3

    References

    • Qi, Xian Liang; Yang, Er Qun; Zhang, Jun Tao; Wang, Tao; Cao, Xiao Ping Chinese Chemical Letters, 2012 , vol. 23, # 6 p. 661 - 664

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H320
Precautionary Statements : P264-P280-P302+P352-P305+P351+P338-P362

Quality Control

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Computational Chemistry Data

  • TPSA   49.41
  • LogP   1.0874
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   1

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