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CS-W001157 4
Total: USD 88.00

4-((tert-Butoxycarbonyl)amino)tetrahydro-2H-pyran-4-carboxylic acid

  • CAS No. 172843-97-9

  • Cat. No. CS-W008506
  • Purity≥97%
  • MDL No.MFCD02683136

*For research and further manufacturing use only, not for direct human use.

4-((tert-Butoxycarbonyl)amino)tetrahydro-2H-pyran-4-carboxylic acid|CS-W008506

Structure of 172843-97-9

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General Information

  • CAS No. 172843-97-9
  • Cat. No. CS-W008506
  • Purity ≥97%
  • MDL No. MFCD02683136
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₉NO₅
  • Molecular Weight 245.27
  • Synonym(s) 4-(Boc-amino)tetrahydropyran-4-carboxylic acid
  • SMILES O=C(C1(NC(OC(C)(C)C)=O)CCOCC1)O

Description

Azido-PEG10-amine is a bifunctional crosslinker with 10 PEG units . The azide group can participate in copper-catalyzed Click Chemistry reactions with alkynes, DBCO and BCN moieties to form triazole groups. The amine group can react with carboxylic acids, activated NHS esters and other carbonyl compounds. The hydrophilic PEG linker increases the water solubility of the compound in aqueous solutions.

Synthesis

  • Route1

    References

    • Journal of the American Chemical Society, , vol. 119, # 49 p. 11807 - 11816
  • Route2

    References

    • Journal of the American Chemical Society, , vol. 119, # 49 p. 11807 - 11816
  • Route3

    References

    • Journal of the American Chemical Society, , vol. 119, # 49 p. 11807 - 11816

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   84.86
  • LogP   1.1449
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   2

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