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CS-W001157 4
Total: USD 88.00

2-((tert-Butoxycarbonyl)amino)-2-methylpropanoic acid

  • CAS No. 30992-29-1

  • Cat. No. CS-W007766
  • Purity≥97%
  • MDL No.MFCD00042973

*For research and further manufacturing use only, not for direct human use.

2-((tert-Butoxycarbonyl)amino)-2-methylpropanoic acid|CS-W007766

Structure of 30992-29-1

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General Information

  • CAS No. 30992-29-1
  • Cat. No. CS-W007766
  • Purity ≥97%
  • MDL No. MFCD00042973
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₇NO₄
  • Molecular Weight 203.24
  • Synonym(s) None
  • SMILES CC(C(O)=O)(C)NC(OC(C)(C)C)=O

Description

This tert-butyl ester of a branched amino acid integrates seamlessly into peptide synthesis workflows. The protected α-amino group enables selective coupling reactions, while the sterically hindered methyl substitution enhances stability and reduces racemization during activation.

Synthesis

  • Route1

    References

    • Kondo; Kimura; Sato; Horimoto Bulletin of the Chemical Society of Japan, 1987 , vol. 60, # 4 p. 1391 - 1397
  • Route2

    References

    • HYUNDAI PHARM CO., LTD.; LEE, Inhee; PYEON, Doohyeok; SHIN, Myounghyeon; HWANG, Jeongun; PARK, Changmin; KIM, Sehoan; CHAE, Heeil; MOON, Soonyoung; KIM, Soyoun; RHEE, Jaekeol Patent: WO2013/19091 A2, 2013 ; Location in patent: Paragraph 613-615 ; WO 2013/019091 A2
  • Route3
    • α-Aminoisobutyric acid|CS-0229297
      62-57-7
    • null|null
      142842-93-1
    • ~44%
    • In-stock
      2-((tert-Butoxycarbonyl)amino)-2-methylpropanoic acid|CS-W007766
      30992-29-1

    References

    • Principia Biopharma Inc.; Goldstein, David Michael Patent: US8673925 B1, 2014 ; Location in patent: Page/Page column 253 ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   75.63
  • LogP   1.3743
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   2

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