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CS-W001157 4
Total: USD 88.00

4-Methoxy-3-nitrobenzaldehyde

  • CAS No. 31680-08-7

  • Cat. No. CS-W008450
  • Purity≥97%
  • MDL No.MFCD00126498

*For research and further manufacturing use only, not for direct human use.

4-Methoxy-3-nitrobenzaldehyde|CS-W008450

Structure of 31680-08-7

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General Information

  • CAS No. 31680-08-7
  • Cat. No. CS-W008450
  • Purity ≥97%
  • MDL No. MFCD00126498
  • Storage 4°C, stored under nitrogen
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₈H₇NO₄
  • Molecular Weight None
  • Synonym(s) 4-Methoxy-3-Nitro Benzaldehyde
  • SMILES O=CC1=CC=C(OC)C([N+]([O-])=O)=C1

Description

4-Methoxy-3-nitrobenzaldehyde features a para-substituted electron-deficient aromatic ring, integrating a methoxy group and a nitro functionality flanking the aldehyde. This combination enables selective reactivity in cross-coupling and condensation reactions, offering enhanced solubility and stability under standard conditions.

Application

4-Methoxy-3-nitrobenzaldehyde serves as a versatile building block in medicinal chemistry and materials science, enabling efficient access to functionalized aromatic scaffolds. Its ortho-directed electrophilic substitution pattern and complementary reactivity of the aldehyde and nitro groups facilitate sequential transformations. The methoxy substituent enhances solubility and modulates electronic effects, while the aldehyde group enables facile imine formation, reductive amination, and coupling reactions. This compound offers bench stability and straightforward purification, making it well-suited for iterative synthesis workflows and scale-up applications.

Safety Information

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Hazard Statements : N/A
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Computational Chemistry Data

  • TPSA   69.44
  • LogP   1.4159
  • H_Acceptors   4
  • H_Donors   0
  • Rotatable_Bonds   3

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