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3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(2-nitrophenyl)propanoic acid

  • CAS No. 171778-06-6

  • Cat. No. CS-0139641
  • Purity≥97%
  • MDL No.MFCD01863202

*For research and further manufacturing use only, not for direct human use.

3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(2-nitrophenyl)propanoic acid|CS-0139641

Structure of 171778-06-6

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General Information

  • CAS No. 171778-06-6
  • Cat. No. CS-0139641
  • Purity ≥97%
  • MDL No. MFCD01863202
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₄H₂₀N₂O₆
  • Molecular Weight 432.43
  • Synonym(s) 3-(9H-fluoren-9-ylmethoxycarbonylamino)-3-(2-nitrophenyl)propanoic Acid
  • SMILES O=C(O)CC(NC(OCC1C2=C(C3=C1C=CC=C3)C=CC=C2)=O)C4=CC=CC=C4[N+]([O-])=O

Description

This fluorenylmethoxycarbonyl-protected amino acid derivative features a sterically hindered, electron-deficient aryl group that enhances coupling efficiency in peptide synthesis. The ortho-nitrophenyl moiety facilitates selective deprotection under mild conditions. Designed for robustness in automated workflows and high-purity requirements.

Synthesis

  • Route1
    • null|null
      28920-43-6
    • In-stock
      3-Amino-3-(2-nitrophenyl)propanoic acid|CS-0312748
      5678-48-8
    • ~97%
    • In-stock
      3-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-3-(2-nitrophenyl)propanoic acid|CS-0139641
      171778-06-6

    References

    • Li, Haishan; Hah, Jung-Mi; Lawrence, David S. Journal of the American Chemical Society, 2008 , vol. 130, # 32 p. 10474 - 10475

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P280-P302+P352

Quality Control

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Computational Chemistry Data

  • TPSA   118.77
  • LogP   4.6493
  • H_Acceptors   5
  • H_Donors   2
  • Rotatable_Bonds   7

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