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CS-W001157 4
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Fmoc-(R)-3-Amino-3-(3-methoxyphenyl)pr opionic acid

  • CAS No. 511272-32-5

  • Cat. No. CS-0179102
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

Fmoc-(R)-3-Amino-3-(3-methoxyphenyl)pr opionic acid|CS-0179102

Structure of 511272-32-5

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General Information

  • CAS No. 511272-32-5
  • Cat. No. CS-0179102
  • Purity ≥98%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₅H₂₃NO₅
  • Molecular Weight 417.45
  • Synonym(s) FMOC-(R)-3-AMINO-3-(3-METHOXY-PHENYL)-PROPIONIC ACID
  • SMILES COC1=CC=CC([C@H](NC(OCC2C3=CC=CC=C3C4=CC=CC=C42)=O)CC(O)=O)=C1

Description

Fmoc-(R)-3-Amino-3-(3-methoxyphenyl)propionic acid is a chiral amino acid derivative featuring a methoxy-substituted phenyl group and a stable Fmoc protecting group. This scaffold enables efficient incorporation into peptide chains under standard coupling conditions, offering enhanced solubility and reduced aggregation during synthesis.

Application

Fmoc-(R)-3-Amino-3-(3-methoxyphenyl)propionic acid serves as a valuable building block for the synthesis of peptide conjugates and bioactive scaffolds. The Fmoc group enables efficient solid-phase peptide synthesis, while the pendant 3-methoxyphenyl moiety offers enhanced solubility and potential for downstream functionalization. Its stability under standard coupling conditions and compatibility with diverse reaction environments make it a practical choice for medicinal chemistry campaigns requiring aromatic side-chain diversity.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P280-P302+P352

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Computational Chemistry Data

  • TPSA   84.86
  • LogP   4.7497
  • H_Acceptors   4
  • H_Donors   2
  • Rotatable_Bonds   7

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