Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

2-(Bis(2-(tert-butoxy)-2-oxoethyl)amino)acetic acid

  • CAS No. 171557-31-6

  • Cat. No. CS-W021426
  • Purity≥95%
  • MDL No.MFCD09833730

*For research and further manufacturing use only, not for direct human use.

2-(Bis(2-(tert-butoxy)-2-oxoethyl)amino)acetic acid|CS-W021426

Structure of 171557-31-6

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 171557-31-6
  • Cat. No. CS-W021426
  • Purity ≥95%
  • MDL No. MFCD09833730
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₄H₂₅NO₆
  • Molecular Weight 303.35
  • Synonym(s) None
  • SMILES O=C(O)CN(CC(OC(C)(C)C)=O)CC(OC(C)(C)C)=O

Description

This acetic acid derivative features a bis(tert-butoxy)oxoethyl-amino substitution, delivering enhanced solubility and stability under standard conditions. The tert-butoxy groups provide steric protection and moisture tolerance, while the amino-acetyl scaffold enables efficient conjugation in bioconjugation workflows.

Application

2-(Bis(2-(tert-butoxy)-2-oxoethyl)amino)acetic acid serves as a versatile bifunctional building block for peptide and macrocycle synthesis, leveraging its two pendant bis(tert-butoxy)ketone groups for selective derivatization. The molecule exhibits robust bench stability and facilitates orthogonal functionalization under mild conditions. Its acetic acid moiety enables conjugation via amide bond formation, while the tert-butyl ester handles are readily cleaved during standard acidic deprotection, simplifying purification and downstream processing.

Synthesis

  • Route1
    • null|null
      171557-57-6
    • ~%
    • In-stock
      2-(Bis(2-(tert-butoxy)-2-oxoethyl)amino)acetic acid|CS-W021426
      171557-31-6

    References

    • Tremblay, Matthew S.; Lee, Minhee; Sames, Dalibor Organic Letters, 2008 , vol. 10, # 1 p. 5 - 8
  • Route2
    • null|null
      1351397-24-4
    • ~%
    • In-stock
      2-(Bis(2-(tert-butoxy)-2-oxoethyl)amino)acetic acid|CS-W021426
      171557-31-6

    References

    • Lee, Byung Chul; Moon, Byung Seok; Kim, Ji Sun; Jung, Jae Ho; Park, Hyun Soo; Katzenellenbogen, John A.; Kim, Sang Eun RSC Advances, 2013 , vol. 3, # 3 p. 782 - 792
  • Route3
    • null|null
      5292-43-3
    • ~%
    • In-stock
      2-(Bis(2-(tert-butoxy)-2-oxoethyl)amino)acetic acid|CS-W021426
      171557-31-6

    References

    • Lee, Byung Chul; Moon, Byung Seok; Kim, Ji Sun; Jung, Jae Ho; Park, Hyun Soo; Katzenellenbogen, John A.; Kim, Sang Eun RSC Advances, 2013 , vol. 3, # 3 p. 782 - 792

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   93.14
  • LogP   1.0564
  • H_Acceptors   6
  • H_Donors   1
  • Rotatable_Bonds   6

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 171557-31-6 sigma171557-31-6 manufacturer171557-31-6 price171557-31-6 structure171557-31-6 SDSbuy 171557-31-6171557-31-6 supplier171557-31-6 uses171557-31-6 molecular weightprice of 171557-31-6171557-31-6 chemical name formula of 171557-31-6
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label