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Structure of 79218-15-8
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tert-Butyl (E)-but-2-enoate is a bench-stable, moisture-tolerant acrylate ester featuring a conjugated trans double bond. This configuration enhances geometric stability and enables reliable participation in cross-coupling and cycloaddition reactions. The tert-butyl group provides steric protection and facilitates clean deprotection under mild acidic conditions.
tert-Butyl (E)-but-2-enoate serves as a stable, bench-ready acrylate equivalent, enabling efficient Michael additions and [2+2] cycloadditions. Its (E)-configured double bond exhibits predictable stereochemistry in conjugate additions, while the tert-butyl ester facilitates straightforward hydrolysis to the corresponding carboxylic acid. The compound demonstrates excellent functional group tolerance and is readily purified by column chromatography, making it ideal for use in complex molecule synthesis and heterocycle construction.
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GHS Pictogram :
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GHS No : GHS02,GHS05
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Signal Word : Danger
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UN#: 3272
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Class : 3
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Packing Group : Ⅲ
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Hazard Statements : H226-H318
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Precautionary Statements : P210-P233-P240-P241-P242-P243-P280-P370+P378-P501
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Lot numbers can be found on the outside label of a product: