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CS-W001157 4
Total: USD 88.00

7-Fluoro-1-indanone

  • CAS No. 651735-59-0

  • Cat. No. CS-D0686
  • Purity≥97%
  • MDL No.MFCD07368749

*For research and further manufacturing use only, not for direct human use.

7-Fluoro-1-indanone|CS-D0686

Structure of 651735-59-0

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General Information

  • CAS No. 651735-59-0
  • Cat. No. CS-D0686
  • Purity ≥97%
  • MDL No. MFCD07368749
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₇FO
  • Molecular Weight 150.15
  • Synonym(s) 7-fluoro-2,3-dihydroinden-1-one
  • SMILES O=C(CC1)C(C1=CC=C2)=C2F

Description

7-Fluoro-1-indanone features a fluorinated indanone scaffold with enhanced electron-withdrawing character due to the ortho-fluorine substituent. This bench-stable ketone integrates readily into synthetic routes requiring aromatic electrophilic substitution or transition-metal-catalyzed coupling, offering improved reactivity and selectivity in complex molecule assembly.

Application

7-Fluoro-1-indanone serves as a versatile building block in medicinal chemistry, enabling efficient construction of fluorinated indanone scaffolds. Its electrophilic carbonyl and electron-deficient aromatic ring facilitate nucleophilic addition and transition-metal-catalyzed coupling reactions. The molecule exhibits excellent bench stability, simplifies purification, and demonstrates broad functional group tolerance in standard synthetic workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   17.07
  • LogP   1.9546
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   0

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