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CS-W001157 4
Total: USD 88.00

6-Methyl-1-indanone

  • CAS No. 24623-20-9

  • Cat. No. CS-W014350
  • Purity≥98%
  • MDL No.MFCD00275729

*For research and further manufacturing use only, not for direct human use.

6-Methyl-1-indanone|CS-W014350

Structure of 24623-20-9

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General Information

  • CAS No. 24623-20-9
  • Cat. No. CS-W014350
  • Purity ≥98%
  • MDL No. MFCD00275729
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₀O
  • Molecular Weight 146.19
  • Synonym(s) 6-methyl-2,3-dihydro-1H-inden-1-one
  • SMILES O=C1CCC2=C1C=C(C)C=C2

Description

6-Methyl-1-indanone is a bicyclic ketone featuring a methyl-substituted indan ring system, offering enhanced stability and solubility in organic solvents. This scaffold serves as a key intermediate in synthesizing bioactive compounds and functional materials due to its rigid, electron-deficient aromatic core and accessible site for electrophilic functionalization.

Application

6-Methyl-1-indanone serves as a versatile building block in synthetic organic chemistry, enabling efficient access to substituted indanones and fused heterocycles. Its methyl-substituted aromatic ring enhances stability and facilitates electrophilic functionalization, while the ketone group supports nucleophilic additions, enolization, and coupling reactions. This compound functions reliably in multistep synthesis, offering predictable reactivity and straightforward purification, making it well-suited for medicinal chemistry campaigns and process development.

Synthesis

  • Route1
    • null|null
      201230-82-2
    • Trimethyl(p-tolylethynyl)silane|CS-0665002
      4186-14-5
    • ~84%
    • In-stock
      6-Methyl-1-indanone|CS-W014350
      24623-20-9

    References

    • Takeuchi, Ryo; Yasue, Hiroyuki Journal of Organic Chemistry, 1993 , vol. 58, # 20 p. 5386 - 5392
  • Route2
    • 2-Bromo-4-methyl-1-vinylbenzene|CS-0971184
      828267-46-5
    • ~78%
    • In-stock
      6-Methyl-1-indanone|CS-W014350
      24623-20-9

    References

    • Wu, Xiongyu; Nilsson, Peter; Larhed, Mats Journal of Organic Chemistry, 2005 , vol. 70, # 1 p. 346 - 349
  • Route3
    • null|null
      103040-39-7
    • ~%
    • In-stock
      6-Methyl-1-indanone|CS-W014350
      24623-20-9

    References

    • WO2009/23757 A1, ; Page/Page column 12 ; WO 2009/023757 A1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   17.07
  • LogP   2.12392
  • H_Acceptors   1
  • H_Donors   0
  • Rotatable_Bonds   0

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