tert-Butyl (morpholin-3-ylmethyl)carbamate

Name: tert-Butyl (morpholin-3-ylmethyl)carbamate
Brand: ChemScene
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CAS No. 169750-75-8
Cat. No. CS-0054197
Purity≥97%
MDL No.None

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Excepted Quantity	$0.00
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tert-Butyl (morpholin-3-ylmethyl)carbamate|CS-0054197

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General Information

CAS No. 169750-75-8
Cat. No. CS-0054197
Purity ≥97%
MDL No. None
Storage RT, protect from light
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₀H₂₀N₂O₃
Molecular Weight 216.28
Synonym(s) tert-butyl N-(Morpholin-3-ylMethyl)carbaMate
SMILES O1CCNC(C1)CNC(OC(C)(C)C)=O

Description

tert-Butyl (morpholin-3-ylmethyl)carbamate features a morpholin-3-ylmethyl scaffold that delivers enhanced solubility and stability in aqueous media. This carbamate derivative serves as a robust protecting group for primary amines, particularly in peptide synthesis and medicinal chemistry applications. The tert-butyl moiety enables mild acidolysis under standard conditions, facilitating selective deprotection without compromising sensitive functional groups. Its bench-stable nature simplifies handling and storage.

Application

tert-Butyl (morpholin-3-ylmethyl)carbamate serves as a stable, bench-friendly morpholine-containing building block for peptide and small-molecule synthesis. It enables selective introduction of the morpholin-3-ylmethyl group under standard deprotection conditions, offering robust functional group tolerance and ease of purification. Its compatibility with amide coupling and reductive amination protocols makes it a practical choice for constructing bioactive scaffolds in medicinal chemistry.

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

TPSA 59.59
LogP 0.4995
H_Acceptors 4
H_Donors 2
Rotatable_Bonds 2

Other Classifications

Building Blocks Skeleton Aliphatic heterocycle compounds Morpholine compounds

Key Words

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tert-Butyl (morpholin-3-ylmethyl)carbamate

CAS No. 169750-75-8

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