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Structure of 167683-93-4
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2-Fluoro-4-methoxyphenol features a fluorine atom at the ortho position and a methoxy group at the para position relative to the phenolic hydroxyl, creating a uniquely polarized aromatic system. This electronic configuration enhances reactivity in electrophilic substitution and facilitates coupling reactions under mild conditions. The compound exhibits good solubility in common organic solvents and maintains stability under standard bench handling protocols. Its dual functionalization enables integration into advanced synthetic intermediates for pharmaceuticals and agrochemicals.
2-Fluoro-4-methoxyphenol serves as a versatile building block in medicinal chemistry, enabling the construction of fluorinated aromatic scaffolds. Its ortho-fluoro and para-methoxy substituents offer complementary reactivity for palladium-catalyzed coupling reactions and electrophilic substitutions. The compound exhibits good bench stability and facilitates straightforward purification, making it well-suited for iterative synthesis workflows in API development.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: