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(S)-N,N-Dimethylpiperidin-3-amine dihydrochloride

  • CAS No. 1630082-61-9

  • Cat. No. CS-0506149
  • Molecule weight201.14
  • Purity≥97%
  • MDL No.MFCD31742795

*For research and further manufacturing use only, not for direct human use.

(S)-N,N-Dimethylpiperidin-3-amine dihydrochloride|CS-0506149

Structure of 1630082-61-9

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General Information

  • CAS No. 1630082-61-9
  • Cat. No. CS-0506149
  • Purity ≥97%
  • MDL No. MFCD31742795
  • Storage Store at room temperature, keep dry and cool
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₈Cl₂N₂
  • Molecular Weight 201.14
  • Synonym(s) None
  • SMILES CN([C@@H]1CNCCC1)C.Cl.Cl

Description

This bench-stable dihydrochloride salt features a chiral piperidin-3-amine core with two methyl groups on nitrogen, enabling efficient incorporation into catalytic systems and bioactive scaffolds. The protonated amine centers enhance solubility in aqueous media while maintaining compatibility with standard synthetic workflows.

Application

(S)-N,N-Dimethylpiperidin-3-amine dihydrochloride serves as a versatile chiral building block in medicinal chemistry, enabling the construction of bioactive heterocycles and peptide-like scaffolds. Its tertiary amine functionality offers favorable solubility and basicity for salt formation, while the (S)-configured piperidine ring provides stereochemical control in asymmetric synthesis. The dihydrochloride salt enhances bench stability and facilitates purification, making it well-suited for use in standard coupling reactions, reductive amination protocols, and transition-metal-catalyzed transformations common in API development.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   15.27
  • LogP   1.1436
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

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