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CS-W001157 4
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rel-tert-Butyl (3S,4R)-4-amino-3-fluoropiperidine-1-carboxylate

  • CAS No. 577691-56-6

  • Cat. No. CS-W001599
  • Purity≥95%
  • MDL No.MFCD12912699

*For research and further manufacturing use only, not for direct human use.

rel-tert-Butyl (3S,4R)-4-amino-3-fluoropiperidine-1-carboxylate|CS-W001599

Structure of 577691-56-6

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General Information

  • CAS No. 577691-56-6
  • Cat. No. CS-W001599
  • Purity ≥95%
  • MDL No. MFCD12912699
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₉FN₂O₂
  • Molecular Weight 218.27
  • Synonym(s) None
  • SMILES F[C@@H]1[C@H](N)CCN(C(OC(C)(C)C)=O)C1

Description

rel-tert-Butyl (3S,4R)-4-amino-3-fluoropiperidine-1-carboxylate is a stereochemically defined amino fluoropiperidine derivative featuring a bench-stable tert-butyl carbamate protecting group. This configuration enables efficient incorporation into complex molecular scaffolds, particularly in the synthesis of bioactive small molecules where precise stereocontrol and metabolic stability are critical.

Application

rel-tert-Butyl (3S,4R)-4-amino-3-fluoropiperidine-1-carboxylate serves as a stereochemically defined building block for the synthesis of fluorinated piperidine scaffolds prevalent in medicinal chemistry. The protected amine and fluorinated stereocenters enable direct incorporation into bioactive molecules via standard coupling and reduction protocols. Its bench-stable nature and compatibility with diverse reaction conditions facilitate efficient route development for drug discovery campaigns.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   55.56
  • LogP   1.2926
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   0

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