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2-{ethyl[(9h-fluoren-9-ylmethoxy)carbonyl]amino}acetic acid

  • CAS No. 162545-29-1

  • Cat. No. CS-0262069
  • Purity≥98%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

2-{ethyl[(9h-fluoren-9-ylmethoxy)carbonyl]amino}acetic acid|CS-0262069

Structure of 162545-29-1

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General Information

  • CAS No. 162545-29-1
  • Cat. No. CS-0262069
  • Purity ≥98%
  • MDL No. None
  • Storage Store at room temperature, keep dry and cool
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₉H₁₉NO₄
  • Molecular Weight 325.36
  • Synonym(s) N-Fmoc-N-ethyl-glycine
  • SMILES O=C(O)CN(CC)C(OCC1C2=C(C3=C1C=CC=C3)C=CC=C2)=O

Description

This fluorenylmethoxycarbonyl-protected amino acid derivative integrates seamlessly into peptide synthesis workflows. The 9H-fluoren-9-ylmethoxy carbonyl group enables efficient, orthogonal protection of amine functionalities, offering high stability under standard reaction conditions and clean deprotection with mild acids.

Application

2-{Ethyl[(9H-fluoren-9-ylmethoxy)carbonyl]amino}acetic acid serves as a versatile protected amino acid building block, enabling efficient peptide synthesis via solid-phase and solution-phase methods. The Fmoc group provides excellent stability under basic conditions and facilitates orthogonal deprotection, while the ethyl ester allows for selective hydrolysis or further functionalization. Its bench-stable, crystalline nature supports straightforward handling and purification, making it ideal for iterative coupling protocols in medicinal chemistry and API development.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   66.84
  • LogP   3.342
  • H_Acceptors   3
  • H_Donors   1
  • Rotatable_Bonds   5

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