Trt-Gly-OH

Name: Trt-Gly-OH
Brand: ChemScene
Availability: InStock
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CAS No. 5893-05-0
Cat. No. CS-0187714
Purity≥95%
MDL No.MFCD00004276

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
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Structure of 5893-05-0

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General Information

CAS No. 5893-05-0
Cat. No. CS-0187714
Purity ≥95%
MDL No. MFCD00004276
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₂₁H₁₉NO₂
Molecular Weight None
Synonym(s) None
SMILES C1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=CC=C3)NCC(=O)O

Description

Trt-Gly-OH is a protected glycine derivative featuring a trityl (Trt) group at the α-amino position and a free carboxylic acid. This configuration enables selective coupling in peptide synthesis, where the Trt moiety provides steric protection and enhanced solubility. The molecule resists racemization during activation and delivers high fidelity in chain elongation.

Synthesis

Route1
- 76-83-5
- 56-40-6
- ~90%
- In-stock
  
  5893-05-0
References
- Sphere Biosystems, Inc. Patent: US6162926 A1, 2000 ;
Route2
- 10065-71-1
- ~45%
- In-stock
  
  5893-05-0
References
- Canle, Moises L.; Clegg, William; Demirtas, Ibrahim; Elsegood, Mark R.J.; Maskill, Howard Journal of the Chemical Society. Perkin Transactions 2, 2000 , # 1 p. 85 - 92
Route3
- 3226-97-9
- ~%
- In-stock
  
  5893-05-0
References
- Synthesis, , # 3 p. 198 - 200

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

TPSA 49.33
LogP 3.6527
H_Acceptors 2
H_Donors 2
Rotatable_Bonds 6

Other Classifications

Bioactive Molecules Peptides

Life Science Amino Acids and their Derivatives Glycine and derivatives

Life Science Amino Acids and their Derivatives N-protected amino acid

Chemical Biology Peptide Chemistry Amino Acid Derivatives

Chemical Biology Pharmaceutical Development and Drug Discovery Research Reagents Peptide Chemistry Amino Acid Derivatives

Chemical Biology Pharmaceutical Development and Drug Discovery Research Peptide Chemistry Amino Acid Derivatives

Biochemistry Biochemicals and Reagents Amino Acids N-Protected Amino Acids

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Trt-Gly-OH

CAS No. 5893-05-0

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