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CS-W001157 4
Total: USD 88.00

Boc-Glycine

  • CAS No. 4530-20-5

  • Cat. No. CS-W008705
  • Purity≥97%
  • MDL No.MFCD00002690

*For research and further manufacturing use only, not for direct human use.

Boc-Glycine|CS-W008705

Structure of 4530-20-5

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General Information

  • CAS No. 4530-20-5
  • Cat. No. CS-W008705
  • Purity ≥97%
  • MDL No. MFCD00002690
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₁₃NO₄
  • Molecular Weight 175.18
  • Synonym(s) N-tert-Butoxycarbonyl-2-aminoacetic acid; NSC 127669
  • SMILES O=C(O)CNC(OC(C)(C)C)=O

Description

Boc-Glycine serves as a key protected amino acid building block in peptide synthesis, featuring a stable tert-butoxycarbonyl group that enables selective N-terminal protection. This bench-stable derivative simplifies coupling reactions and facilitates efficient deprotection under mild acidic conditions.

Synthesis

  • Route1

    References

    • UNIVERSITEIT ANTWERPEN; FOX CHASE CANCER CENTER; JANSEN, Koen; DE MEESTER, Ingrid; HEIRBAUT, Leen; CHENG, Jonathan D; JOOSSENS, Jurgen; AUGUSTYNS, Koen; VAN DER VEKEN, Pieter Patent: WO2013/107820 A1, 2013 ; Location in patent: Page/Page column 42 ;
  • Route2
    • null|null
      17790-86-2
    • ~87%
    • In-stock
      Boc-Glycine|CS-W008705
      4530-20-5

    References

    • Voelkert, Martin; Koul, Surrinder; Mueller, Gernot H.; Lehnig, Manfred; Waldmann, Herbert Journal of Organic Chemistry, 2002 , vol. 67, # 20 p. 6902 - 6910
  • Route3
    • null|null
      98015-52-2
    • Glycine, 99%|CS-1269057
      56-40-6
    • ~88%
    • In-stock
      Boc-Glycine|CS-W008705
      4530-20-5

    References

    • Barcelo, Gerard; Senet, Jean-Pierre; Sennyey, Gerard Journal of Organic Chemistry, 1985 , vol. 50, # 20 p. 3951 - 3953

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   75.63
  • LogP   0.5957
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   2

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