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CS-W001157 4
Total: USD 88.00

2,2-Dimethoxy-2-phenylacetophenone

  • CAS No. 24650-42-8

  • Cat. No. CS-0150663
  • Purity≥98%
  • MDL No.MFCD00008475

*For research and further manufacturing use only, not for direct human use.

2,2-Dimethoxy-2-phenylacetophenone|CS-0150663

Structure of 24650-42-8

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General Information

  • CAS No. 24650-42-8
  • Cat. No. CS-0150663
  • Purity ≥98%
  • MDL No. MFCD00008475
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₆H₁₆O₃
  • Molecular Weight 256.30
  • Synonym(s) Photoinitiator-651
  • SMILES COC(C1=CC=CC=C1)(C(=O)C2=CC=CC=C2)OC

Description

2,2-Dimethoxy-2-phenylacetophenone (DMPA) can be used as a photoinitiator:For the photopolymerization of methacrylate monomers in thick sections(~2mm).In the preparation of UV-curing silicone rubber with excellent mechanical properties and thermal stability via thiol-ene reaction.It can also be used as a starting material to prepare a water-soluble supramolecular-structured photoinitiator which is more efficient than DMPA.

Application

2,2-Dimethoxy-2-phenylacetophenone serves as a stable, bench-ready synthon for the construction of functionalized diaryl ketones and heterocyclic scaffolds. Its ortho-dimethoxy group enables selective deprotection and facilitates electrophilic substitution or coupling reactions under mild conditions. The molecule exhibits excellent stability and ease of purification, making it a practical building block in medicinal chemistry and process development workflows.

Synthesis

  • Route1

    References

    • Ciba-Geigy Corporation Patent: US4190602 A1, 1980 ;
  • Route2

    References

    • Ciba-Geigy Corporation Patent: US4190602 A1, 1980 ;
  • Route3
    • In-stock
      Benzil|CS-0012125
      134-81-6
    • null|null
      80-48-8
    • ~%
    • In-stock
      2,2-Dimethoxy-2-phenylacetophenone|CS-0150663
      24650-42-8

    References

    • US4287367 A1, ;

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07,GHS08
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H373-H412
Precautionary Statements : P260-P264-P270-P273-P330-P501

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Computational Chemistry Data

  • TPSA   35.53
  • LogP   3.0151
  • H_Acceptors   3
  • H_Donors   0
  • Rotatable_Bonds   5

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