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CS-W001157 4
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Bromo-PEG8-Boc

  • CAS No. 1623792-00-6

  • Cat. No. CS-0114586
  • Purity≥97%
  • MDL No.MFCD26793748

*For research and further manufacturing use only, not for direct human use.

Bromo-PEG8-Boc|CS-0114586

Structure of 1623792-00-6

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General Information

  • CAS No. 1623792-00-6
  • Cat. No. CS-0114586
  • Purity ≥97%
  • MDL No. MFCD26793748
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₃H₄₅BrO₁₀
  • Molecular Weight 561.50
  • Synonym(s) None
  • SMILES O=C(OC(C)(C)C)CCOCCOCCOCCOCCOCCOCCOCCOCCBr

Description

Bromo-PEG8-Boc features a bromide handle flanked by a hydrophilic PEG8 spacer and a tert-butoxycarbonyl protecting group. This combination enables site-specific conjugation under mild conditions while maintaining stability during storage and handling. The molecule integrates seamlessly into peptide synthesis, polymer functionalization, and bioconjugation workflows where controlled reactivity and solubility are essential.

Application

Bromo-PEG8-Boc serves as a versatile bifunctional building block for the synthesis of PEGylated compounds, enabling efficient conjugation via nucleophilic substitution. The bromide functionality reacts readily with amines and thiols under mild conditions, while the Boc group provides orthogonal protection for primary amines. Its eight-ethylene glycol units confer enhanced solubility and stability in aqueous media, facilitating purification and downstream applications in drug delivery and bioconjugation.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   100.14
  • LogP   2.2459
  • H_Acceptors   10
  • H_Donors   0
  • Rotatable_Bonds   26

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