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Imidazo[1,2-b]pyridazine-2-carboxylic acid

  • CAS No. 160911-42-2

  • Cat. No. CS-0006625
  • Purity≥98%
  • MDL No.MFCD08235229

*For research and further manufacturing use only, not for direct human use.

Imidazo[1,2-b]pyridazine-2-carboxylic acid|CS-0006625

Structure of 160911-42-2

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General Information

  • CAS No. 160911-42-2
  • Cat. No. CS-0006625
  • Purity ≥98%
  • MDL No. MFCD08235229
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₇H₅N₃O₂
  • Molecular Weight 163.13
  • Synonym(s) Imidazo[1,2-b]pyridazine-2-carboxylic acid (9CI)
  • SMILES O=C(O)C1=CN2C(C=CC=N2)=N1

Description

Imidazo[1,2-b]pyridazine-2-carboxylic acid features a fused heterocyclic core with a carboxylic acid group at the 2-position, enabling direct conjugation in synthetic transformations. This scaffold combines enhanced stability with high reactivity at the carboxylate site, facilitating efficient coupling reactions in medicinal chemistry and materials science applications.

Application

Imidazo[1,2-b]pyridazine-2-carboxylic acid serves as a versatile heterocyclic building block for medicinal chemistry and materials science applications. Its carboxylic acid functionality enables direct derivatization via amide coupling or esterification, while the fused imidazo-pyridazine core offers enhanced metabolic stability and favorable pharmacophore geometry. The compound exhibits good bench stability and facilitates efficient purification by crystallization or chromatography, supporting its use in multi-step synthesis workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   67.49
  • LogP   0.4275
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   1

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