(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-7-(tert-butoxy)-7-oxoheptanoic acid

Name: (S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-7-(tert-butoxy)-7-oxoheptanoic acid
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 159751-46-9
Cat. No. CS-0101030
Purity≥96%
MDL No.MFCD08166552

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-7-(tert-butoxy)-7-oxoheptanoic acid|CS-0101030

Structure of 159751-46-9

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 159751-46-9
Cat. No. CS-0101030
Purity ≥96%
MDL No. MFCD08166552
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₂₆H₃₁NO₆
Molecular Weight 453.53
Synonym(s) (S)-2-FMOC-AMINO-HEPTANEDIOIC ACID 7-TERT-BUTYL ESTER
SMILES O=C(O)[C@@H](NC(OCC1C2=C(C3=C1C=CC=C3)C=CC=C2)=O)CCCCC(OC(C)(C)C)=O

Description

This fluorenylmethoxycarbonyl-protected amino acid derivative features a sterically hindered tert-butoxy group and a reactive ketone moiety, enabling selective conjugation in peptide synthesis. The C-terminal carboxylic acid facilitates efficient coupling under standard conditions, while the bench-stable fluorenylmethyl carbamate safeguards the amine during iterative assembly.

Application

(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-7-(tert-butoxy)-7-oxoheptanoic acid serves as a robust chiral building block for peptide synthesis, enabling efficient N-terminal protection and side-chain functionalization. The fluorenylmethoxycarbonyl (Fmoc) group ensures high stability and orthogonal deprotection under mild basic conditions. The tert-butoxy carbonyl moiety provides a readily cleavable auxiliary for selective transformations, while the β-ketoacid functionality facilitates downstream cyclizations and heterocycle formation. Its bench-stable solid form simplifies handling and purification in multi-step syntheses.

Synthesis

Route1
- 868754-94-3
- ~94%
- In-stock
  
  159751-46-9
References
- Ryan, Shannon J.; Zhang, Yongda; Kennan, Alan J. Organic Letters, 2005 , vol. 7, # 21 p. 4765 - 4767
Route2
- In-stock
  
  14036-55-6
- ~%
- In-stock
  
  159751-46-9
References
- Ryan, Shannon J.; Zhang, Yongda; Kennan, Alan J. Organic Letters, 2005 , vol. 7, # 21 p. 4765 - 4767
Route3
- In-stock
  
  146549-21-5
- ~%
- In-stock
  
  159751-46-9
References
- Ryan, Shannon J.; Zhang, Yongda; Kennan, Alan J. Organic Letters, 2005 , vol. 7, # 21 p. 4765 - 4767

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 101.93
LogP 4.8804
H_Acceptors 5
H_Donors 2
Rotatable_Bonds 9

Other Classifications

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Chemical Biology Peptide Chemistry Amine Protection

Chemical Biology Peptide Chemistry Unnatural Amino Acid Derivatives

Key Words

159751-46-9 sigma159751-46-9 manufacturer159751-46-9 price159751-46-9 structure159751-46-9 SDSbuy 159751-46-9159751-46-9 supplier159751-46-9 uses159751-46-9 molecular weightprice of 159751-46-9159751-46-9 chemical name formula of 159751-46-9

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

(S)-2-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-7-(tert-butoxy)-7-oxoheptanoic acid

CAS No. 159751-46-9

Recommended Products

General Information

Description

Application

Synthesis

References

References

References

Safety Information

Quality Control

Computational Chemistry Data

Similar Products

Other Classifications

Recently Viewed Products

Key Words