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CS-W001157 4
Total: USD 88.00

(S)-4-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-5-(benzyloxy)-5-oxopentanoic acid

  • CAS No. 122350-52-1

  • Cat. No. CS-0059148
  • Purity≥96%
  • MDL No.None

*For research and further manufacturing use only, not for direct human use.

(S)-4-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-5-(benzyloxy)-5-oxopentanoic acid|CS-0059148

Structure of 122350-52-1

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General Information

  • CAS No. 122350-52-1
  • Cat. No. CS-0059148
  • Purity ≥96%
  • MDL No. None
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₇H₂₅NO₆
  • Molecular Weight 459.49
  • Synonym(s) F-moc-Glu-OBz
  • SMILES O=C(O)CC[C@@H](C(OCC1=CC=CC=C1)=O)NC(OCC2C3=C(C4=C2C=CC=C4)C=CC=C3)=O

Description

This fluorenylmethoxy carbonyl-protected amino acid derivative features a bench-stable, electron-rich fluoren-9-yl group that facilitates efficient purification and orthogonal deprotection. The benzyloxy-bearing side chain enables selective functionalization in peptide synthesis workflows, while the oxo-functionalized pentanoic acid moiety provides a handle for conjugation and derivatization under standard conditions.

Synthesis

  • Route1
    • null|null
      154672-63-6
    • ~90%
    • In-stock
      (S)-4-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-5-(benzyloxy)-5-oxopentanoic acid|CS-0059148
      122350-52-1

    References

    • Journal of Organic Chemistry, , vol. 59, # 4 p. 929 - 931
  • Route2

    References

    • Journal of Medicinal Chemistry, , vol. 37, # 18 p. 2958 - 2969
  • Route3
    • null|null
      100-39-0
    • ~%
    • In-stock
      (S)-4-((((9H-Fluoren-9-yl)methoxy)carbonyl)amino)-5-(benzyloxy)-5-oxopentanoic acid|CS-0059148
      122350-52-1

    References

    • Journal of Medicinal Chemistry, , vol. 37, # 18 p. 2958 - 2969

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   101.93
  • LogP   4.5019
  • H_Acceptors   5
  • H_Donors   2
  • Rotatable_Bonds   9

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