Lot numbers can be found on the outside label of a product:
2-(2-(((Benzyloxy)carbonyl)amino)acetamido)acetic acid
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CAS No. 2566-19-0
- Cat. No. CS-W009447
- Purity≥97%
- MDL No.MFCD00037783
*For research and further manufacturing use only, not for direct human use.
Structure of 2566-19-0
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General Information
- CAS No. 2566-19-0
- Cat. No. CS-W009447
- Purity ≥97%
- MDL No. MFCD00037783
- Storage 4°C
- Shipping Room temperature in continental US; may vary elsewhere.
- Molecular Formula C₁₂H₁₄N₂O₅
- Molecular Weight None
- Synonym(s) None
- SMILES O=C(O)CNC(CNC(OCC1=CC=CC=C1)=O)=O
Description
This protected amino acid derivative features a benzyl ester-protected carboxylic acid and a carbamoyl-linked side chain, enabling direct incorporation into peptide synthesis workflows. The benzyloxy carbonyl group provides orthogonal protection, allowing selective deprotection under mild conditions. Designed for use in solid-phase peptide synthesis, this reagent delivers high coupling efficiency and minimal epimerization.
Application
2-(2-(((Benzyloxy)carbonyl)amino)acetamido)acetic acid serves as a stable, bench-ready building block for peptide synthesis, enabling efficient N-terminal protection and orthogonal deprotection. Its carbamate functionality facilitates selective coupling reactions and compatibility with standard amino acid activation protocols, while the benzyloxy carbonyl group offers robust protection under common synthetic conditions.
Synthesis
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Route1
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In-stock
556-50-3 -
501-53-1 - ~60%
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In-stock
2566-19-0
References
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US6020526 A1, ;
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Route2
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In-stock
1138-80-3 - ~%
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In-stock
2566-19-0
References
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Justus Liebigs Annalen der Chemie, , vol. 572, p. 190,193
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Route3
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In-stock
3005-87-6 - ~%
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In-stock
2566-19-0
References
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Chemische Berichte, , vol. 92, p. 1675,1677 Justus Liebigs Annalen der Chemie, , vol. 572, p. 96,105 Recueil des Travaux Chimiques des Pays-Bas, , vol. 78, p. 487,499 Chemische Berichte, , vol. 91, p. 1073,1079 Justus Liebigs Annalen der Chemie, , vol. 575, p. 217,230 Australian Journal of Chemistry, , vol. 11, p. 360,364
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Safety Information
Download SDS|
GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Quality Control
Computational Chemistry Data
- TPSA 104.73
- LogP 0.1136
- H_Acceptors 4
- H_Donors 3
- Rotatable_Bonds 6
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Key Words
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