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CS-W001157 4
Total: USD 88.00

Z-Glu-OBzl

  • CAS No. 3705-42-8

  • Cat. No. CS-W008255
  • Purity≥98%
  • MDL No.MFCD00077013

*For research and further manufacturing use only, not for direct human use.

Z-Glu-OBzl|CS-W008255

Structure of 3705-42-8

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General Information

  • CAS No. 3705-42-8
  • Cat. No. CS-W008255
  • Purity ≥98%
  • MDL No. MFCD00077013
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₀H₂₁NO₆
  • Molecular Weight 371.38
  • Synonym(s) None
  • SMILES O=C(O)CC[C@@H](C(OCC1=CC=CC=C1)=O)NC(OCC2=CC=CC=C2)=O

Description

Z-Glu-OBzl features a protected glutamic acid residue with a benzyl ester and benzyloxycarbonyl (Z) group, enabling stable incorporation into peptide synthesis. This configuration supports efficient coupling under standard conditions while maintaining compatibility with orthogonal deprotection strategies in complex sequence assembly.

Synthesis

  • Route1

    References

    • de Beer, Roseri J.A.C.; Zarzycka, Barbara; Mariman, Michiel; Amatdjais-Groenen, Helene I.V.; Mulders, Marc J.; Quaedflieg, Peter J.L.M.; van Delft, Floris L.; Nabuurs, Sander B.; Rutjes, Floris P.J.T. ChemBioChem, 2012 , vol. 13, # 9 p. 1319 - 1326
  • Route2
    • In-stock
      H-Glu-Obzl|CS-W009487
      13030-09-6
    • null|null
      501-53-1
    • ~%
    • In-stock
      Z-Glu-OBzl|CS-W008255
      3705-42-8

    References

    • Sachs; Brand Journal of the American Chemical Society, 1953 , vol. 75, p. 4608
  • Route3

    References

    • Goldschmidt,S. et al. Chemische Berichte, 1964 , vol. 97, p. 2434 - 2438

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

  • TPSA   101.93
  • LogP   2.8896
  • H_Acceptors   5
  • H_Donors   2
  • Rotatable_Bonds   9

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