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Structure of 153556-55-9
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4-Chloro-2-fluoro-3-methylbenzoic acid features a trifunctional aromatic core with orthogonal reactivity, enabling direct integration into bioactive scaffolds. The ortho-halogenated framework enhances electrophilic substitution potential, while the methyl group provides steric modulation. This bench-stable derivative offers high functional group tolerance and delivers precise electronic tuning for medicinal chemistry applications.
4-Chloro-2-fluoro-3-methylbenzoic acid serves as a versatile building block in medicinal chemistry, enabling the synthesis of bioactive heterocycles and pharmaceutical intermediates. Its ortho-fluoro and meta-chloro substituents provide enhanced metabolic stability and modulate electronic properties, while the carboxylic acid group facilitates direct coupling reactions. The molecule exhibits good bench stability and compatibility with standard functional group transformations, making it well-suited for iterative synthesis workflows.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: