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CS-W001157 4
Total: USD 88.00

1-(3-Chlorophenyl)cyclopropanecarboxylic acid

  • CAS No. 124276-34-2

  • Cat. No. CS-0038546
  • Purity≥97%
  • MDL No.None
  • HazMat Fee +

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    Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

    If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

    Type
    HazMat Fee
    Excepted Quantity $0.00
    FedEx Limited Quantities Ground $0.00
    Hazmat Ground shipping $50.00+
    Inaccessible (Haz class 6.1 or 9), Domestic $68.00+
    Accessible (Haz class 3, 4, 5 or 8), Domestic $158.00+
    Inaccessible (Haz class 6.1 or 9), International $108.00+
    Accessible (Haz class 3, 4, 5 or 8), International $238.00+

    An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

    There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

1-(3-Chlorophenyl)cyclopropanecarboxylic acid|CS-0038546

Structure of 124276-34-2

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Description

This cyclopropanecarboxylic acid derivative features a 3-chlorophenyl group attached to the cyclopropyl ring, delivering enhanced lipophilicity and metabolic stability. The carboxylic acid functionality enables direct coupling in peptide synthesis or derivatization for medicinal chemistry applications. Designed for robust performance under standard bench conditions, this compound serves as a key building block in bioactive molecule development.

Application

1-(3-Chlorophenyl)cyclopropanecarboxylic acid serves as a valuable building block in medicinal chemistry, enabling the synthesis of bioactive molecules through standard functional group manipulations. Its cyclopropane core imparts conformational rigidity, while the ortho-chlorinated aryl moiety offers enhanced metabolic stability and favorable pharmacokinetic properties. The carboxylic acid functionality facilitates direct coupling reactions, esterification, or amide formation, supporting efficient route development for API candidates. Bench-stable and readily purified by recrystallization, it functions reliably in multi-step syntheses.

General Information

  • CAS No. 124276-34-2
  • Cat. No. CS-0038546
  • Purity ≥97%
  • MDL No. None
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₉ClO₂
  • Molecular Weight 196.63
  • Synonym(s) 1-(3-chlorophenyl)cyclopropane-1-carboxylic acid
  • SMILES C1=CC(=CC(=C1)C2(CC2)C(=O)O)Cl

Computational Chemistry Data

  • TPSA   37.3
  • LogP   2.4562
  • H_Acceptors   1
  • H_Donors   1
  • Rotatable_Bonds   2

Safety Information

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GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H319
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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