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CS-W001157 4
Total: USD 88.00

2-(4-BOC-Piperazino)-3-nitropyridine Palbociclib Impurity

  • CAS No. 153473-24-6

  • Cat. No. CS-0229210
  • Purity≥98%
  • MDL No.MFCD09028514

*For research and further manufacturing use only, not for direct human use.

2-(4-BOC-Piperazino)-3-nitropyridine Palbociclib  Impurity|CS-0229210

Structure of 153473-24-6

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General Information

  • CAS No. 153473-24-6
  • Cat. No. CS-0229210
  • Purity ≥98%
  • MDL No. MFCD09028514
  • Storage Sealed in dry,2-8℃
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₄H₂₀N₄O₄
  • Molecular Weight 308.33
  • Synonym(s) Tert-butyl 4-(3-nitropyridin-2-yl)piperazine-1-carboxylate
  • SMILES O=C(N1CCN(C2=NC=CC=C2[N+]([O-])=O)CC1)OC(C)(C)C

Synthesis

  • Route1

    References

    • ASTRAZENECA AB Patent: WO2008/112440 A1, 2008 ; Location in patent: Page/Page column 46 ; WO 2008/112440 A1
  • Route2

    References

    • Chemical and Pharmaceutical Bulletin, , vol. 49, # 11 p. 1406 - 1411
  • Route3

    References

    • Bioorganic and Medicinal Chemistry Letters, , vol. 15, # 21 p. 4867 - 4871

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P330-P362+P364-P405-P501

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Computational Chemistry Data

  • TPSA   88.81
  • LogP   2.0469
  • H_Acceptors   6
  • H_Donors   0
  • Rotatable_Bonds   2

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