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CS-W001157 4
Total: USD 88.00

tert-Butyl 4-(5-nitropyridin-2-yl)piperazine-1-carboxylate

  • CAS No. 193902-78-2

  • Cat. No. CS-0048258
  • Purity≥97%
  • MDL No.MFCD07369779

*For research and further manufacturing use only, not for direct human use.

tert-Butyl 4-(5-nitropyridin-2-yl)piperazine-1-carboxylate|CS-0048258

Structure of 193902-78-2

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General Information

  • CAS No. 193902-78-2
  • Cat. No. CS-0048258
  • Purity ≥97%
  • MDL No. MFCD07369779
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₄H₂₀N₄O₄
  • Molecular Weight 308.33
  • Synonym(s) 1-boc-4-(5-nitro-2-pyridyl)piperazine
  • SMILES CC(C)(C)OC(=O)N1CCN(CC1)C1=NC=C(C=C1)[N+]([O-])=O

Synthesis

  • Route1
    • In-stock
      2-Bromo-5-nitropyridine|CS-W007858
      4487-59-6
    • N-Boc-piperazine Olaparib Impurity|CS-0214004
      57260-71-6
    • ~90%
    • In-stock
      tert-Butyl 4-(5-nitropyridin-2-yl)piperazine-1-carboxylate|CS-0048258
      193902-78-2

    References

    • WARNER-LAMBERT COMPANY, LLC Patent: US2005/182078 A1, 2005 ; Location in patent: Page/Page column 9; 12 ; US 20050182078 A1
  • Route2
    • In-stock
      2-Chloro-5-nitropyridine|CS-W013280
      4548-45-2
    • N-Boc-piperazine Olaparib Impurity|CS-0214004
      57260-71-6
    • ~98%
    • In-stock
      tert-Butyl 4-(5-nitropyridin-2-yl)piperazine-1-carboxylate|CS-0048258
      193902-78-2

    References

    • Ting, Pauline C.; Lee, Joe F.; Zorn, Nicolas; Kim, Hyunjin M.; Aslanian, Robert G.; Lin, Mingxiang; Smith, Michelle; Walker, Scott S.; Cook, John; Van Heek, Margaret; Lachowicz, Jean Bioorganic and Medicinal Chemistry Letters, 2013 , vol. 23, # 4 p. 985 - 988
  • Route3

    References

    • Liu, Yu; Liu, Zining; Cao, Xufeng; Liu, Xin; He, Huili; Yang, Yushe Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 16 p. 4779 - 4783

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS06
Signal Word : Danger
UN#: 2811
Class : 6.1
Packing Group : Ⅲ
Hazard Statements : H301
Precautionary Statements : P264-P270-P330-P405-P501

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Computational Chemistry Data

  • TPSA   88.81
  • LogP   2.0469
  • H_Acceptors   6
  • H_Donors   0
  • Rotatable_Bonds   2

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