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CS-W001157 4
Total: USD 88.00

Bis-PEG6-NHS ester

  • CAS No. 1526718-98-8

  • Cat. No. CS-0107647
  • Purity≥97%
  • MDL No.MFCD24539464

*For research and further manufacturing use only, not for direct human use.

Bis-PEG6-NHS ester|CS-0107647

Structure of 1526718-98-8

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General Information

  • CAS No. 1526718-98-8
  • Cat. No. CS-0107647
  • Purity ≥97%
  • MDL No. MFCD24539464
  • Storage -20°C, sealed storage, away from moisture
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₂₄H₃₆N₂O₁₄
  • Molecular Weight 576.55
  • Synonym(s) None
  • SMILES O=C(ON1C(CCC1=O)=O)CCOCCOCCOCCOCCOCCOCCC(ON2C(CCC2=O)=O)=O

Description

Bis-PEG6-NHS ester features two PEG6 chains flanking a reactive NHS ester group, enabling efficient conjugation to primary amines under physiological conditions. This bifunctional linker offers enhanced solubility and spacer length for bioconjugation applications, facilitating site-specific labeling of proteins and peptides with minimal steric interference.

Application

Bis-PEG6-NHS ester serves as a versatile, water-soluble crosslinking reagent for protein and biomolecule conjugation. The two NHS ester groups enable efficient coupling to primary amines under physiological conditions, while the PEG6 spacer provides enhanced solubility and reduced non-specific binding. Its stability in aqueous environments and clean reaction profile facilitate straightforward purification and consistent conjugation yields in bioconjugation workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P264-P280-P302+P352-P362

Quality Control

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Computational Chemistry Data

  • TPSA   182.74
  • LogP   -0.9194
  • H_Acceptors   14
  • H_Donors   0
  • Rotatable_Bonds   23

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