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CS-W001157 4
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tert-Butyl (R)-(1-hydroxybutan-2-yl)carbamate

  • CAS No. 150736-71-3

  • Cat. No. CS-0094053
  • Purity≥95%
  • MDL No.MFCD04974273

*For research and further manufacturing use only, not for direct human use.

tert-Butyl (R)-(1-hydroxybutan-2-yl)carbamate|CS-0094053

Structure of 150736-71-3

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General Information

  • CAS No. 150736-71-3
  • Cat. No. CS-0094053
  • Purity ≥95%
  • MDL No. MFCD04974273
  • Storage Store at room temperature
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₉H₁₉NO₃
  • Molecular Weight 189.25
  • Synonym(s) N-Boc-(R)-(+)-2-amino-1-butanol
  • SMILES O=C(OC(C)(C)C)N[C@@H](CO)CC

Description

tert-Butyl (R)-(1-hydroxybutan-2-yl)carbamate is a chiral building block featuring a stereogenic center at the C1 position, stabilized by a bench-stable tert-butoxycarbonyl (Boc) protecting group. The pendant hydroxyl moiety enables selective derivatization and integration into complex molecular architectures. This configurationally defined intermediate supports asymmetric synthesis workflows requiring controlled stereochemical integrity.

Synthesis

  • Route1

    References

    • Dullin, Anja; Dufrasne, Francois; Gelbcke, Michael; Gust, Ronald Archiv der Pharmazie, 2004 , vol. 337, # 12 p. 654 - 667
  • Route2
    • null|null
      251325-57-2
    • ~%
    • In-stock
      (S)-tert-Butyl (1-hydroxybutan-2-yl)carbamate|CS-0153911
      150736-72-4
    • In-stock
      tert-Butyl (R)-(1-hydroxybutan-2-yl)carbamate|CS-0094053
      150736-71-3

    References

    • Burk, Mark J.; Johnson, Nicholas B.; Lee, Jeffrey R. Tetrahedron Letters, 1999 , vol. 40, # 36 p. 6685 - 6688
  • Route3
    • null|null
      121056-95-9
    • ~%
    • In-stock
      tert-Butyl (R)-(1-hydroxybutan-2-yl)carbamate|CS-0094053
      150736-71-3

    References

    • Burk, Mark J.; Johnson, Nicholas B.; Lee, Jeffrey R. Tetrahedron Letters, 1999 , vol. 40, # 36 p. 6685 - 6688

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS05,GHS06
Signal Word : Danger
UN#: 2923
Class : 8 (6.1)
Packing Group : Ⅲ
Hazard Statements : H301-H314
Precautionary Statements : P260-P264-P270-P280-P301+P330+P331-P304+P340-P363-P405-P501

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Computational Chemistry Data

  • TPSA   58.56
  • LogP   1.282
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   3

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