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CS-W001157 4
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N-(4-Chloro-5-iodo-7H-pyrrolo[2,3-d]pyriMidin-2-yl)-2,2-diMethyl propanaMide

  • CAS No. 149765-16-2

  • Cat. No. CS-W023094
  • Purity≥97%
  • MDL No.MFCD11109808

*For research and further manufacturing use only, not for direct human use.

N-(4-Chloro-5-iodo-7H-pyrrolo[2,3-d]pyriMidin-2-yl)-2,2-diMethyl propanaMide|CS-W023094

Structure of 149765-16-2

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General Information

  • CAS No. 149765-16-2
  • Cat. No. CS-W023094
  • Purity ≥97%
  • MDL No. MFCD11109808
  • Storage -20°C, sealed storage, away from moisture and light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₁H₁₂ClIN₄O
  • Molecular Weight 378.60
  • Synonym(s) N-(4-Chloro-5-iodo-7H-pyrrolo[2,3-d]pyrimidin-2-yl)-2,2-dimethylpropionamide
  • SMILES CC(C)(C)C(NC1=NC(Cl)=C2C(NC=C2I)=N1)=O

Synthesis

  • Route1
    • N-(4-Chloro-7H-pyrrolo[2,3-d]pyrimidin-2-yl)-2,2-dimethylpropionamide|CS-W006652
      149765-15-1
    • ~85%
    • In-stock
      N-(4-Chloro-5-iodo-7H-pyrrolo[2,3-d]pyriMidin-2-yl)-2,2-diMethyl propanaMide|CS-W023094
      149765-16-2

    References

    • Seela, Frank; Peng, Xiaohua Synthesis, 2004 , # 8 p. 1203 - 1210
  • Route2
    • N-(4-Oxo-4,7-dihydro-1H-pyrrolo[2,3-d]pyrimidin-2-yl)pivalamide|CS-0099164
      137281-08-4
    • ~%
    • In-stock
      N-(4-Chloro-5-iodo-7H-pyrrolo[2,3-d]pyriMidin-2-yl)-2,2-diMethyl propanaMide|CS-W023094
      149765-16-2

    References

    • Journal of Medicinal Chemistry, , vol. 46, # 4 p. 591 - 600
  • Route3

    References

    • Synthesis, , # 8 p. 1203 - 1210

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   70.67
  • LogP   3.2005
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   1

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