6-Chloro-7-deazaguanine

Name: 6-Chloro-7-deazaguanine
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 84955-31-7
Cat. No. CS-W019601
Purity≥97%
MDL No.MFCD07369229

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

Structure of 84955-31-7

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 84955-31-7
Cat. No. CS-W019601
Purity ≥97%
MDL No. MFCD07369229
Storage -20°C, stored under nitrogen
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₆H₅ClN₄
Molecular Weight 168.58
Synonym(s) None
SMILES NC1=NC(Cl)=C2C(NC=C2)=N1

Description

6-Chloro-7-deazaguanine is a purine analog featuring a chlorine substituent at the 6-position and a nitrogen-to-carbon substitution at the 7-position, enhancing metabolic stability. This structural modification improves resistance to enzymatic degradation while maintaining base-pairing fidelity, making it valuable for nucleoside analog synthesis in antiviral and anticancer research.

Application

6-Chloro-7-deazaguanine serves as a valuable purine scaffold for medicinal chemistry and nucleoside analog synthesis, offering enhanced metabolic stability and tunable base-pairing properties. Its chloro substitution at the C6 position enables selective derivatization in late-stage functionalization, while the 7-deaza modification improves resistance to enzymatic degradation. The compound exhibits good bench stability and facilitates efficient incorporation into oligonucleotides and antiviral prodrug candidates through standard coupling protocols.

Synthesis

Route1
- In-stock
  
  7355-55-7
- ~79%
- In-stock
  
  84955-31-7
References
- Liebigs Annalen der Chemie, , p. 15 - 19
Route2
- 52133-67-2
- ~%
- In-stock
  
  84955-31-7
References
- Russian Journal of Bioorganic Chemistry, , vol. 21, # 11 p. 756 - 761 Bioorganicheskaya Khimiya, , vol. 21, # 11 p. 874 - 880
Route3
- 84981-48-6
- ~%
- In-stock
  
  84955-31-7
References
- Liebigs Annalen der Chemie, , # 1 p. 137 - 146

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H319
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 67.59
LogP 1.1935
H_Acceptors 3
H_Donors 2
Rotatable_Bonds 0

Other Classifications

Building Blocks Functional Group Amine

Building Blocks Functional Group Chloride

Building Blocks Skeleton Aromatic heterocycle compounds Pyrrole compounds

Building Blocks Skeleton Aromatic heterocycle compounds Pyrimidine compounds

Key Words

6-Chloro-7-deazaguanine sigma6-Chloro-7-deazaguanine manufacturer6-Chloro-7-deazaguanine price6-Chloro-7-deazaguanine structure6-Chloro-7-deazaguanine SDSbuy 6-Chloro-7-deazaguanine6-Chloro-7-deazaguanine supplier6-Chloro-7-deazaguanine uses6-Chloro-7-deazaguanine molecular weightprice of 6-Chloro-7-deazaguanine6-Chloro-7-deazaguanine chemical name formula of 6-Chloro-7-deazaguanine

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

6-Chloro-7-deazaguanine

CAS No. 84955-31-7

Recommended Products

General Information

Description

Application

Synthesis

References

References

References

Safety Information

Quality Control

Computational Chemistry Data

Similar Products

Other Classifications

Recently Viewed Products

Key Words