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CS-W001157 4
Total: USD 88.00

7-Deazahypoxanthine

  • CAS No. 3680-71-5

  • Cat. No. CS-M1987
  • Purity≥98%
  • MDL No.MFCD08234923

*For research and further manufacturing use only, not for direct human use.

7-Deazahypoxanthine|CS-M1987

Structure of 3680-71-5

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General Information

  • CAS No. 3680-71-5
  • Cat. No. CS-M1987
  • Purity ≥98%
  • MDL No. MFCD08234923
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₅N₃O
  • Molecular Weight 135.12
  • Synonym(s) None
  • SMILES OC1=C2C=CNC2=NC=N1

Description

7-Deazahypoxanthine features a modified purine scaffold with nitrogen at position 7 replaced by carbon, enhancing metabolic stability and altering electronic properties. This structural refinement supports its role in nucleoside analog synthesis, where it imparts resistance to enzymatic degradation while maintaining base-pairing fidelity. The compound serves as a key building block in antiviral and anticancer research.

Application

7-Deazahypoxanthine serves as a key purine scaffold for medicinal chemistry applications, offering enhanced metabolic stability compared to natural purines. It functions as a versatile building block in the synthesis of nucleoside analogs and kinase inhibitors, with demonstrated compatibility in standard coupling and functionalization reactions. The absence of the nitrogen at position 7 improves solubility and reduces undesired side reactivity, facilitating purification and downstream derivatization.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H317-H319
Precautionary Statements : P261-P264-P272-P280-P302+P352-P363-P501

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Computational Chemistry Data

  • TPSA   61.8
  • LogP   0.6635
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   0

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