Fmoc-Asp-OMe

Name: Fmoc-Asp-OMe
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 145038-52-4
Cat. No. CS-W022722
Purity≥97%
MDL No.MFCD03701473

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

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General Information

CAS No. 145038-52-4
Cat. No. CS-W022722
Purity ≥97%
MDL No. MFCD03701473
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₂₀H₁₉NO₆
Molecular Weight 369.37
Synonym(s) None
SMILES O=C(O)C[C@H](NC(OCC1C2=C(C3=C1C=CC=C3)C=CC=C2)=O)C(OC)=O

Description

Fmoc-Asp-OMe features a protected aspartic acid residue with orthogonal functionality for peptide synthesis. The Fmoc group enables base-labile N-terminal deprotection, while the methyl ester stabilizes the C-terminal carboxylate. This combination facilitates efficient coupling and selective modification in solid-phase workflows, offering reliable handling and compatibility with standard protocols.

Application

Fmoc-Asp-OMe serves as a key building block in solid-phase peptide synthesis, offering orthogonal protection for both the α-amino and side-chain carboxyl groups. The Fmoc group enables efficient base-labile deprotection, while the methyl ester prevents unwanted side reactions during coupling. Its bench-stable nature and compatibility with standard coupling reagents facilitate reliable incorporation into peptide sequences, particularly in the synthesis of acidic or complex peptide scaffolds.

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

TPSA 101.93
LogP 2.5414
H_Acceptors 5
H_Donors 2
Rotatable_Bonds 6

Other Classifications

Bioactive Molecules Peptides

Life Science Amino Acids and their Derivatives Aspartic acid and derivatives

Building Blocks Functional Group Fmoc

Chemical Biology Peptide Chemistry Amine Protection

Chemical Biology Peptide Chemistry Unnatural Amino Acid Derivatives

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Fmoc-Asp-OMe

CAS No. 145038-52-4

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