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CS-W001157 4
Total: USD 88.00

Z-Asp-OMe

  • CAS No. 4668-42-2

  • Cat. No. CS-W010044
  • Purity≥98%
  • MDL No.MFCD00083277

*For research and further manufacturing use only, not for direct human use.

Z-Asp-OMe|CS-W010044

Structure of 4668-42-2

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General Information

  • CAS No. 4668-42-2
  • Cat. No. CS-W010044
  • Purity ≥98%
  • MDL No. MFCD00083277
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₃H₁₅NO₆
  • Molecular Weight 281.26
  • Synonym(s) None
  • SMILES O=C(C[C@H](NC(OCC1=CC=CC=C1)=O)C(OC)=O)O

Description

Z-Asp-OMe features a protected aspartic acid side chain with a benzyloxycarbonyl (Z) group and methyl ester terminus, enabling stable incorporation into peptide synthesis. This derivative facilitates efficient coupling reactions under standard conditions while minimizing side reactions, offering reliable access to aspartate-containing sequences in both solid-phase and solution-phase workflows.

Application

Z-Asp-OMe serves as a key chiral building block in peptide synthesis, enabling efficient construction of Asp-containing sequences with high stereocontrol. The Z (benzyloxycarbonyl) group provides robust protection of the α-amino function, while the methyl ester facilitates selective activation and coupling under standard conditions. Its bench-stable solid form and compatibility with common coupling reagents make it ideal for both manual and automated synthesis workflows.

Safety Information

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GHS Pictogram :
GHS No : GHS05,GHS07
Signal Word : Danger
UN#: 3261
Class : 8
Packing Group : Ⅲ
Hazard Statements : H302+H332-H318
Precautionary Statements : P261-P264-P270-P271-P280-P304+P340-P330-P501

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Computational Chemistry Data

  • TPSA   101.93
  • LogP   0.9291
  • H_Acceptors   5
  • H_Donors   2
  • Rotatable_Bonds   6

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