Boc-D-Asp-OMe

Name: Boc-D-Asp-OMe
Brand: ChemScene
Availability: InStock
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CAS No. 137130-65-5
Cat. No. CS-0154574
Purity≥97%
MDL No.MFCD03094776

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Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

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General Information

CAS No. 137130-65-5
Cat. No. CS-0154574
Purity ≥97%
MDL No. MFCD03094776
Storage Store at room temperature
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₀H₁₇NO₆
Molecular Weight 247.25
Synonym(s) D-Aspartic acid, N-[(1,1-dimethylethoxy)carbonyl]-, 1-methyl ester
SMILES CC(C)(OC(N[C@@H](C(OC)=O)CC(O)=O)=O)C

Description

Boc-D-Asp-OMe features a protected D-aspartic acid side chain with a methyl ester group, enabling stable incorporation into peptide sequences. The Boc group ensures efficient deprotection under mild acidic conditions, while the methyl ester enhances solubility and compatibility in synthetic workflows. This derivative supports robust peptide synthesis with minimal epimerization risk.

Application

Boc-D-Asp-OMe serves as a key chiral building block for the synthesis of D-aspartic acid-containing peptides and peptidomimetics. The Boc group provides reliable protection of the α-amino function, while the methyl ester facilitates selective hydrolysis or derivatization. This derivative exhibits excellent bench stability, simplifies purification, and enables efficient coupling in standard solid-phase and solution-phase peptide synthesis workflows.

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

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Computational Chemistry Data

TPSA 101.93
LogP 0.5274
H_Acceptors 5
H_Donors 2
Rotatable_Bonds 4

Other Classifications

Building Blocks Functional Group Boc

Building Blocks Functional Group Ester

Building Blocks Skeleton Chiral compounds Chiral Building Blocks

Chemical Biology Peptide Chemistry Amine Protection

Chemical Biology Peptide Chemistry Unnatural Amino Acid Derivatives

Key Words

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Boc-D-Asp-OMe

CAS No. 137130-65-5

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