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CS-W001157 4
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Di-tert-butyl iminodicarboxylate

  • CAS No. 51779-32-9

  • Cat. No. CS-D0755
  • Purity≥96%
  • MDL No.MFCD00043309

*For research and further manufacturing use only, not for direct human use.

Di-tert-butyl iminodicarboxylate|CS-D0755

Structure of 51779-32-9

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General Information

  • CAS No. 51779-32-9
  • Cat. No. CS-D0755
  • Purity ≥96%
  • MDL No. MFCD00043309
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₁₉NO₄
  • Molecular Weight 217.26
  • Synonym(s) None
  • SMILES O=C(OC(C)(C)C)NC(OC(C)(C)C)=O

Description

D-(+)-Glucose is a monosaccharide which is the main source of energy in the form of ATP for living organisms. The effect of adding glucose as a supplement to the infection media of Cryptosporidium parvum oocysts has been studied. The polymer-bound glucose template has been demonstrated to be useful in the multi-step parallel synthesis of various compounds.D-(+)-Glucose has been used as a standard for the estimation of total sugar in hydrolyzed starch by phenol-sulfuric acid method.It has been used in the preparation of the following liquid media for culturing yeast cells:CM glucose broth minus HIS (histidine)CM glucose broth minus URA (uracil)CM glucose broth minus TRP (tryptophan)

Application

Di-tert-butyl iminodicarboxylate serves as a robust diester building block for the synthesis of heterocycles and peptide-like scaffolds. Its tert-butyl ester groups offer excellent bench stability and ease of removal under mild acidic conditions, enabling efficient deprotection without side reactions. The molecule functions effectively in Mannich-type cyclizations and acts as a key precursor in the construction of nitrogen-containing ring systems, particularly in the development of cyclic amine intermediates used in medicinal chemistry.

Synthesis

  • Route1
    • null|null
      78476-42-3
    • null|null
      75-65-0
    • ~53%
    • In-stock
      Di-tert-butyl iminodicarboxylate|CS-D0755
      51779-32-9

    References

    • Bunnenberg, Rolf; Jochims, Johannes C. Chemische Berichte, 1981 , vol. 114, # 6 p. 2064 - 2074
  • Route2
    • null|null
      1070-19-5
    • ~%
    • In-stock
      Di-tert-butyl iminodicarboxylate|CS-D0755
      51779-32-9

    References

    • Abramovitch,R.A. et al. Journal of Organic Chemistry, 1974 , vol. 39, p. 2513 - 2516
  • Route3

    References

    • Carpino,L.A. Journal of Organic Chemistry, 1964 , vol. 29, p. 2820 - 2824

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H315-H319-H335
Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362-P405-P501

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Computational Chemistry Data

  • TPSA   64.63
  • LogP   2.4462
  • H_Acceptors   4
  • H_Donors   1
  • Rotatable_Bonds   0

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