Tel:

Email:

EN
Cat. No. Size / Unit Price Qty
CS-W001157 4
Total: USD 88.00

4,6-Dichloronicotinamide

  • CAS No. 70593-57-6

  • Cat. No. CS-W019071
  • Purity≥98%
  • MDL No.MFCD01646073

*For research and further manufacturing use only, not for direct human use.

4,6-Dichloronicotinamide|CS-W019071

Structure of 70593-57-6

Please choose your location and provide accurate information for you
Size Stock
Price Quantity

* Please select Quantity before adding items.

General Information

  • CAS No. 70593-57-6
  • Cat. No. CS-W019071
  • Purity ≥98%
  • MDL No. MFCD01646073
  • Storage 4°C
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₆H₄Cl₂N₂O
  • Molecular Weight 191.02
  • Synonym(s) 4,6-DICHLORO-NICOTINAMIDE
  • SMILES O=C(N)C1=CN=C(Cl)C=C1Cl

Description

4,6-Dichloronicotinamide delivers a highly electron-deficient pyridine scaffold ideal for coupling reactions in agrochemical and pharmaceutical synthesis. The dual chlorine substituents enhance reactivity at the amide nitrogen and provide strategic handles for further functionalization under mild conditions. This bench-stable compound integrates efficiently into complex molecular architectures with predictable regiochemistry.

Application

4,6-Dichloronicotinamide serves as a versatile building block in medicinal chemistry, enabling efficient construction of heterocyclic scaffolds through nucleophilic substitution and coupling reactions. Its dual chloro substituents at the 4- and 6-positions provide orthogonal reactivity for sequential functionalization, while the amide group offers stability and compatibility with diverse reaction conditions. The compound exhibits excellent bench stability and facilitates straightforward purification, making it well-suited for high-throughput synthesis and process development workflows.

Synthesis

  • Route1

    References

    • Boehringer Ingelheim International GmbH Patent: US2006/217417 A1, 2006 ; Location in patent: Page/Page column 12; 13 ;
  • Route2

    References

    • WO2010/129802 A1, ; Page/Page column 207 ; WO 2010/129802 A1

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

  • TPSA   55.98
  • LogP   1.4873
  • H_Acceptors   2
  • H_Donors   1
  • Rotatable_Bonds   1

Other Classifications

Recently Viewed Products

Leave US a Message
Upload Pictures

Key Words

  • 4,6-Dichloronicotinamide sigma4,6-Dichloronicotinamide manufacturer4,6-Dichloronicotinamide price4,6-Dichloronicotinamide structure4,6-Dichloronicotinamide SDSbuy 4,6-Dichloronicotinamide4,6-Dichloronicotinamide supplier4,6-Dichloronicotinamide uses4,6-Dichloronicotinamide molecular weightprice of 4,6-Dichloronicotinamide4,6-Dichloronicotinamide chemical name formula of 4,6-Dichloronicotinamide
This product is not sold in the region.
Confirm
How to get a Lot Number

Lot numbers can be found on the outside label of a product:

ChemScene Label