tert-Butyl 7-(hydroxymethyl)-2-azaspiro[3.5]nonane-2-carboxylate

Name: tert-Butyl 7-(hydroxymethyl)-2-azaspiro[3.5]nonane-2-carboxylate
Brand: ChemScene
Availability: InStock
Rating: 5 (1 reviews)

CAS No. 1434141-69-1
Cat. No. CS-0048149
Purity≥96%
MDL No.MFCD27956901

HazMat Fee +

HazMat Fee

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it. There is a HazMat shipping fee for each item that qualifies as a dangerous good, except in the following scenarios:

The shipment is processed through FedEx Ground under the Limited Quantity option.

Each bottle is packed as an Excepted Quantity, with a maximum of 1g for items in class 6.1 packing group I or II, and up to 25g for all other hazardous materials.

If shipping is charged to your FedEx account, the HazMat fee will be billed directly by the courier. Otherwise, the fee will be included on your invoice. To help you avoid the HazMat fee, we can package a 5g order of a class 6.1 packing group I or II material as five separate 1g units, and a 100g order of any other dangerous good as four 25g units. This packaging adjustment will be made unless you instruct otherwise on your purchase order. Below, you will find the fee schedule from FedEx for handling hazardous materials.

Type	HazMat Fee
Excepted Quantity	$0.00
FedEx Limited Quantities Ground	$0.00
Hazmat Ground shipping	$50.00+
Inaccessible (Haz class 6.1 or 9), Domestic	$68.00+
Accessible (Haz class 3, 4, 5 or 8), Domestic	$158.00+
Inaccessible (Haz class 6.1 or 9), International	$108.00+
Accessible (Haz class 3, 4, 5 or 8), International	$238.00+

An item is classified as a dangerous good if our website displays Hazardous Material (HazMat) information for it.

There is a HazMat shipping fee for each item that qualifies as a dangerous good. Please contact our quotation team via email to confirm the details.

*For research and further manufacturing use only, not for direct human use.

tert-Butyl 7-(hydroxymethyl)-2-azaspiro[3.5]nonane-2-carboxylate|CS-0048149

Structure of 1434141-69-1

Size

Price

Quantity

* Please select Quantity before adding items.

General Information

CAS No. 1434141-69-1
Cat. No. CS-0048149
Purity ≥96%
MDL No. MFCD27956901
Storage 4°C
Shipping Room temperature in continental US; may vary elsewhere.
Molecular Formula C₁₄H₂₅NO₃
Molecular Weight 255.36
Synonym(s) None
SMILES O=C(OC(C)(C)C)N1CC2(C1)CCC(CO)CC2

Description

tert-Butyl 7-(hydroxymethyl)-2-azaspiro[3.5]nonane-2-carboxylate features a spirocyclic scaffold with a pendant hydroxymethyl group, enabling direct functionalization in synthetic routes. The tert-butyl ester provides stability and ease of removal under mild acidic conditions. This compound serves as a key intermediate in the synthesis of bioactive aza-spirocycles, particularly in medicinal chemistry applications requiring stereoselective access to complex nitrogen-containing ring systems.

Application

tert-Butyl 7-(hydroxymethyl)-2-azaspiro[3.5]nonane-2-carboxylate serves as a versatile spirocyclic building block for medicinal chemistry and natural product synthesis. The hydroxymethyl group enables selective oxidation to aldehyde or carboxylic acid, while the tert-butyl ester allows for mild deprotection under acidic conditions. Its rigid spiro framework provides defined stereochemistry and enhances metabolic stability, facilitating efficient access to complex nitrogen-containing scaffolds via standard functional group interconversions.

Safety Information

Download SDS

GHS Pictogram :	GHS No : GHS07
Signal Word : Warning	UN#: N/A
Class : N/A	Packing Group : N/A
Hazard Statements : H315-H319
Precautionary Statements : P264-P280-P302+P352-P362

Quality Control

To search for quality control of cas , please enter both the product number and the lot/batch number.

Computational Chemistry Data

TPSA 49.77
LogP 2.406
H_Acceptors 3
H_Donors 1
Rotatable_Bonds 1

Other Classifications

Building Blocks Functional Group Alcohol

Building Blocks Skeleton Aliphatic heterocycle compounds Azetidine compounds

Building Blocks Skeleton Spirol Rings compounds

Key Words

1434141-69-1 sigma1434141-69-1 manufacturer1434141-69-1 price1434141-69-1 structure1434141-69-1 SDSbuy 1434141-69-11434141-69-1 supplier1434141-69-1 uses1434141-69-1 molecular weightprice of 1434141-69-11434141-69-1 chemical name formula of 1434141-69-1

Salutation:	*Country or Region:
*Applicant Name:	*Organization Name:
*Email Address:	Quantity:
CAS NO. :	Product Name:
Remarks:
Upload Pictures

CAS.No.		Product Name
Applicant Name *		Email Address *
Phone Number *		Organization Name*
Country or Region*		Quantity*
Remarks:

Product Name:
Cat. No.: .		CAS NO. :
Quantity:

tert-Butyl 7-(hydroxymethyl)-2-azaspiro[3.5]nonane-2-carboxylate

CAS No. 1434141-69-1

Recommended Products