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Structure of 142253-58-5
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tert-Butyl 3-(cyanomethyl)azetidine-1-carboxylate features a strained azetidine core bearing a cyanomethyl group and a robust tert-butyl carbamate protecting group. This combination enables direct incorporation into complex heterocyclic scaffolds, offering enhanced stability during synthetic manipulations and compatibility with diverse reaction conditions.
tert-Butyl 3-(cyanomethyl)azetidine-1-carboxylate serves as a versatile building block for the synthesis of nitrogen-containing heterocycles, enabling efficient access to azetidine-based scaffolds. The cyanomethyl group facilitates subsequent transformations such as nitrile reduction or cyclization, while the tert-butyl ester provides bench stability and ease of purification. It functions effectively in standard coupling reactions and offers good functional group tolerance, making it suitable for medicinal chemistry and process-scale applications.
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H302-H315-H319-H335
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Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501
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Lot numbers can be found on the outside label of a product: