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Structure of 1463502-41-1
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tert-Butyl 3-(prop-2-yn-1-yl)azetidine-1-carboxylate features a strained azetidine ring bearing a propargyl substituent, enabling efficient conjugation via copper-catalyzed alkyne-azide cycloaddition. The tert-butyl carbamate group provides stability and ease of removal under mild acidic conditions, facilitating downstream functionalization in medicinal chemistry applications.
tert-Butyl 3-(prop-2-yn-1-yl)azetidine-1-carboxylate serves as a versatile building block for the synthesis of azetidine-containing scaffolds in medicinal chemistry. The propargyl group enables facile Cu-catalyzed azide-alkyne cycloaddition (CuAAC), while the tert-butyl carbamate provides orthogonal protection. Its bench-stable nature and compatibility with diverse reaction conditions facilitate efficient access to functionalized heterocycles and complex molecular architectures.
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GHS Pictogram :
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GHS No : GHS07
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Signal Word : Warning
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UN#: N/A
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Class : N/A
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Packing Group : N/A
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Hazard Statements : H315-H319-H335
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Precautionary Statements : P261-P264-P271-P280-P302+P352-P304+P340-P362+P364-P405-P501
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Lot numbers can be found on the outside label of a product: