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CS-W001157 4
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(S)-tert-Butyl (pyrrolidin-2-ylmethyl)carbamate

  • CAS No. 141774-70-1

  • Cat. No. CS-W003340
  • Purity≥95%
  • MDL No.MFCD06796572

*For research and further manufacturing use only, not for direct human use.

(S)-tert-Butyl (pyrrolidin-2-ylmethyl)carbamate|CS-W003340

Structure of 141774-70-1

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General Information

  • CAS No. 141774-70-1
  • Cat. No. CS-W003340
  • Purity ≥95%
  • MDL No. MFCD06796572
  • Storage 4°C, protect from light
  • Shipping Room temperature in continental US; may vary elsewhere.
  • Molecular Formula C₁₀H₂₀N₂O₂
  • Molecular Weight 200.28
  • Synonym(s) tert-butyl [(2S)-pyrrolidin-2-ylmethyl]carbamate
  • SMILES O=C(OC(C)(C)C)NC[C@@H]1CCCN1

Description

(S)-tert-Butyl (pyrrolidin-2-ylmethyl)carbamate is a chiral building block featuring a pyrrolidin-2-ylmethyl scaffold with a bench-stable tert-butyl carbamate protecting group. This configuration enables selective incorporation into peptide sequences and complex heterocycles, where the nitrogen functionality supports efficient coupling reactions under mild conditions.

Application

(S)-tert-Butyl (pyrrolidin-2-ylmethyl)carbamate serves as a chiral auxiliary and protected amine synthon in asymmetric synthesis. Its robust tert-butyl carbamate group enables stable, bench-friendly handling and orthogonal deprotection under mild acidic conditions. The pyrrolidin-2-ylmethyl moiety facilitates stereoselective functionalization and acts as a versatile building block for nitrogen-containing heterocycles and bioactive scaffolds in medicinal chemistry workflows.

Safety Information

Download SDS
GHS Pictogram :
GHS No : GHS07
Signal Word : Warning
UN#: N/A
Class : N/A
Packing Group : N/A
Hazard Statements : H302-H315-H319-H335
Precautionary Statements : P261-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P330-P362+P364-P403+P233-P405-P501

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Computational Chemistry Data

  • TPSA   50.36
  • LogP   1.2631
  • H_Acceptors   3
  • H_Donors   2
  • Rotatable_Bonds   2

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